Construction and Evaluation of a Nomogram Model Related to Abdominal Aortic Aneurysm Rupture and Exploration of Its Potential Mechanism

The risk score of the nomogram model could discriminate AAA rupture, and it was also linked to the poor prognosis of AAA patients. Moreover, T cells CD4 memory activated may be related to AAA rupture by involving the immune environment.Clinical ImpactThis study identified risk factors associated with AAA rupture, constructed a risk model, and explored its underlying mechanisms. High-risk scores derived from the nomogram model were negatively associated with patient outcomes, indicating that this risk model can serve as a stratification tool to guide individualized intervention strategies. The risk model utilizing fewer indicators can be employed for initial screening, followed by application of composite scores for high-risk patients to optimize clinical decision-making and enhance the efficiency of healthcare resource allocation.