Economic evaluations of the primary prevention programs for viral hepatitis-related liver disease and liver cancer: a systematic literature review

Primary prevention strategies for viral hepatitis-related liver disease are generally cost-effective, particularly in high-risk populations. Universal screening and early treatment were associated with improved health outcomes, including reductions in hepatocellular carcinoma, cirrhosis, and liver-related mortality. However, significant variations in methodological approaches limit direct comparability across studies and across countries.

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Publication Details

Journal
Cost Effectiveness and Resource Allocation
Published
2026-02-19
DOI
https://doi.org/10.1186/s12962-026-00727-y
Primary Topic
Hepatitis C virus research
Type
article
Field-Weighted Citation Impact
0.00
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article

Economic evaluations of the primary prevention programs for viral hepatitis-related liver disease and liver cancer: a systematic literature review

J. Richard George, Ann Carrigan, Shenghan Cai, Putu Novi Arfirsta Dharmayani et al.
Cost Effectiveness and Resource Allocation
Hepatitis C virus research
article

Economic evaluations of the primary prevention programs for viral hepatitis-related liver disease and liver cancer: a systematic literature review

J. Richard George, Ann Carrigan, Shenghan Cai, Putu Novi Arfirsta Dharmayani, Stephen Goodall, Shalini Wijekulasuriya, Yvonne Zurynski, Milena Lewandowska, Rose Boutros, Amany Zekry
article en

Abstract

Primary prevention strategies for viral hepatitis-related liver disease are generally cost-effective, particularly in high-risk populations. Universal screening and early treatment were associated with improved health outcomes, including reductions in hepatocellular carcinoma, cirrhosis, and liver-related mortality. However, significant variations in methodological approaches limit direct comparability across studies and across countries.

Cost Effectiveness and Resource AllocationVol. 24(1)
University of Technology Sydney (AU), The University of Sydney (AU), Sutherland Hospital (AU), Westmead Hospital (AU), St George Hospital (AU), Sydney Local Health District (AU), Westmead Institute for Medical Research (AU), South Western Sydney Local Health District (AU), Macquarie University (AU)
Openalex Percentile: Top 50%
Hepatitis C virus research
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Economic evaluations of the primary prevention programs for viral hepatitis-related liver disease and liver cancer: a systematic literature review — J. Richard George, Ann Carrigan, et al. · Cost Effectiveness and Resource Allocation (2026) | TGRS Research Map | TGRS