Clinical study on gray matter volume reduction, gait disorders, and fall risk in patients with Alzheimer’s disease
The preliminary findings of this study indicate that BMI, stride length variability, and medication burden may be associated with fall risk and reduced gray matter volume in specific brain region may be a potential neuroanatomical basis for increased risk of falls in AD patients, which need to be further validated in larger cohorts.
Authors
- Yihan Yang
- Yi Qiao (ORCID: https://orcid.org/0000-0002-4667-9018)
- Xu Yang (ORCID: https://orcid.org/0000-0002-3615-3063)
- Y. Liu
- Shan Wang
- Ya Wen
- Xuelin Wang
- Kexin Cheng
- Wenjie Gao
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
- Hebei Meteorological Bureau (CN)
- Hebei Rehabilitation Hospital (JP)
- Ministry of Education (KR)
- Neurological Surgery (US)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2026-02-19
- DOI
- https://doi.org/10.3389/fneur.2026.1737591
- Primary Topic
- Balance, Gait, and Falls Prevention
- Type
- article
- Field-Weighted Citation Impact
- 0.00