Management of infertility in women with hypothalamic hypogonadotropic hypogonadism: an expert opinion
When pulsatile GnRH therapy is not available, and to ensure the effective treatment of female infertility due to FHA (with or without PCOS) or hypothalamic CHH, we advise physicians to optimise stimulation with exogenous gonadotropins according to the cause of hypothalamic hypogonadotropic hypogonadism. In all cases, providing luteal phase support by optimising corpus luteum function is mandatory.
Authors
- Maria Katsogiannou (ORCID: https://orcid.org/0000-0002-1002-7261)
- S. Dubourdieu
- S. Christin-Maitre
- Geoffroy Robin
- Michel De Vos
- Lorraine Maitrot-Mantelet
- Bérengère Kiehl-Bigot
Institutions
- Université de Lille (FR)
- Centre Hospitalier Universitaire de Lille (FR)
- Sorbonne Université (FR)
- Lille’s Cardiology Hospital (FR)
- Hôpital Cochin (FR)
- Hôpital Saint-Antoine (FR)
- Universitair Ziekenhuis Brussel (BE)
- IMT Atlantique (FR)
- Ferring Pharmaceuticals (France) (FR)
- Institut Cochin (FR)
Publication Details
- Journal
- Reproductive Biology and Endocrinology
- Published
- 2026-02-19
- DOI
- https://doi.org/10.1186/s12958-026-01535-y
- Primary Topic
- Hypothalamic control of reproductive hormones
- Type
- article
- Field-Weighted Citation Impact
- 0.00