Establishment of a Large‐Scale <scp>PDX</scp> Library of Head and Neck Cancers for Functional Precision Oncology
The FXeL represents a robust and scalable platform for investigating HNC biology and therapeutic response. Despite limitations such as stromal remodeling and the absence of an immune microenvironment, these models provide valuable translational insights and support the advancement of functional precision oncology.
Authors
- A Yoshida (ORCID: https://orcid.org/0009-0004-5865-109X)
- Yasuyoshi Mizutani
- Hisayuki Kato (ORCID: https://orcid.org/0000-0002-8101-7423)
- Kenji Kawada (ORCID: https://orcid.org/0000-0003-4336-6937)
- Hisano Yanagi
- Motoshi Suzuki (ORCID: https://orcid.org/0000-0003-0682-5006)
- Maki Kurimoto
- Ichiro Tateya (ORCID: https://orcid.org/0000-0003-4737-4811)
- Tomoki Kuki
- Seiji Yamada (ORCID: https://orcid.org/0000-0002-9770-2425)
- Tetsuya Takimoto (ORCID: https://orcid.org/0009-0009-3008-8078)
- C. Yagi
- Atsushi Enomoto
- Miki Takabayashi
- Hideyuki Saya
- Yoshitake Kiryu
- Miho Ishikawa
- Takashi Watanabe
Institutions
- Fujita Health University (JP)
- Nagoya University (JP)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/cam4.71521
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Keio University
- Ministry of Education, Culture, Sports, Science and Technology
- Fujita Health University
- Japan Society for the Promotion of Science