FAM216A Promotes Hepatocellular Carcinoma Proliferation and Invasion through the PLK1/ERK Signaling Pathway
FAM216A is overexpressed in HCC tissues and is associated with poor clinical outcomes. Mechanistically, FAM216A promotes aggressive tumor behavior by activating the PLK1/ERK signaling pathway.
Authors
- Kaihuan Yu
- Weixing Wang (ORCID: https://orcid.org/0000-0002-3854-0083)
- Wei Wang
- Weiguo Tang
- Peng Ma
- Ying Hao
- Zuo Muo
- Yuefeng Zhang
Institutions
- Fudan University (CN)
- Wuhan University (CN)
- Minhang District Central Hospital (CN)
- Shanghai Municipal Commission of Health and Family Planning (CN)
- Renmin Hospital of Wuhan University (CN)
Publication Details
- Journal
- Genetic Testing and Molecular Biomarkers
- Published
- 2026-02-19
- DOI
- https://doi.org/10.1177/19450265261417993
- Primary Topic
- Angiogenesis and VEGF in Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00