MicroRNA-451 Modulates Autophagy-Related Signaling with Relevance to Renal Fibrosis in an Accelerated Mouse Model of Diabetic Kidney Disease
miR-451 overexpression attenuates renal fibrosis and modulates autophagy-associated pathways in diabetic kidney disease, independent of metabolic control, highlighting miR-451 as a potential therapeutic target for diabetic kidney disease.
Authors
- Neal Mohit
- Kanwal K. Gambhir (ORCID: https://orcid.org/0000-0002-0394-4280)
- Maurice B. Fluitt (ORCID: https://orcid.org/0000-0002-6963-3311)
- Sadaf Ghaderzadeh
- Chidera Obiwuma
- Baiyee-Ndang Agbor-Baiyee
- Bradley Bobga
Institutions
- Howard University (US)
- Georgetown University (US)
Publication Details
- Journal
- Current Issues in Molecular Biology
- Published
- 2026-02-19
- DOI
- https://doi.org/10.3390/cimb48020223
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00