Maximal motor unit firing rates decline with amyotrophic lateral sclerosis progression

Maximal firing rates analysis has the potential to serve as a quantitative clinical biomarker of neuromotor system degeneration, complementing global functional scales in clinical monitoring.

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Publication Details

Journal
Clinical Neurophysiology
Published
2026-02-19
DOI
https://doi.org/10.1016/j.clinph.2026.2111697
Primary Topic
Amyotrophic Lateral Sclerosis Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Maximal motor unit firing rates decline with amyotrophic lateral sclerosis progression

João Saldanha Henkin, Ehsan Esmaili Shandiz, Gabriel Fernandes, Lucas BR Orssatto et al.
Clinical Neurophysiology
Amyotrophic Lateral Sclerosis Research
article

Maximal motor unit firing rates decline with amyotrophic lateral sclerosis progression

João Saldanha Henkin, Ehsan Esmaili Shandiz, Gabriel Fernandes, Lucas BR Orssatto, Gabriel S. Trajano, Robert D. Henderson, Pamela A. McCombe, Matheus D. Pinto
article en

Abstract

Maximal firing rates analysis has the potential to serve as a quantitative clinical biomarker of neuromotor system degeneration, complementing global functional scales in clinical monitoring.

Clinical NeurophysiologyVol. 185
Edith Cowan University (AU), Queensland University of Technology (AU), The University of Queensland (AU), Royal Brisbane and Women's Hospital (AU), Southern Cross University (AU)
Openalex Percentile: Top 54%
Amyotrophic Lateral Sclerosis Research
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Maximal motor unit firing rates decline with amyotrophic lateral sclerosis progression — João Saldanha Henkin, Ehsan Esmaili Shandiz, et al. · Clinical Neurophysiology (2026) | TGRS Research Map | TGRS