The Dual Mechanism of Action of CO-005 Overcomes CD20 Resistance in Diffuse Large B-Cell Lymphoma

These findings position CO-005 as a mechanistically distinct and immunologically active therapeutic with the potential to overcome limitations of both CD20- and CD47-directed therapies and expand treatment options for B-cell lymphoma.

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Publication Details

Journal
ImmunoTargets and Therapy
Published
2026-02-01
DOI
https://doi.org/10.2147/itt.s572396
Primary Topic
Phagocytosis and Immune Regulation
Type
article
Field-Weighted Citation Impact
0.00
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article

The Dual Mechanism of Action of CO-005 Overcomes CD20 Resistance in Diffuse Large B-Cell Lymphoma

Seham Skah, Kjetil Hestdal, Nina Richartz, Hanne R. Hagland et al.
ImmunoTargets and Therapy
Phagocytosis and Immune Regulation
article

The Dual Mechanism of Action of CO-005 Overcomes CD20 Resistance in Diffuse Large B-Cell Lymphoma

Seham Skah, Kjetil Hestdal, Nina Richartz, Hanne R. Hagland, Øystein Åmellem, Sittana Matar, Rolf D. Pettersen, Liza Moltu
article en

Abstract

These findings position CO-005 as a mechanistically distinct and immunologically active therapeutic with the potential to overcome limitations of both CD20- and CD47-directed therapies and expand treatment options for B-cell lymphoma.

ImmunoTargets and TherapyVol. Volume 15
University of Stavanger (NO)
Good health and well-being
Openalex Percentile: Top 48%
Phagocytosis and Immune Regulation
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The Dual Mechanism of Action of CO-005 Overcomes CD20 Resistance in Diffuse Large B-Cell Lymphoma — Seham Skah, Kjetil Hestdal, et al. · ImmunoTargets and Therapy (2026) | TGRS Research Map | TGRS