Microwave ablation combined with dendritic cells enhances CD8+ T cell activation in rechallenged tumor mouse model
Our findings highlight a synergistic antitumor mechanism of MWA and DC-based therapy through cDC1 activation and CD8⁺ T cell enhancement, providing a promising strategy to reduce tumor recurrence after MWA.
Authors
- Shanlong Zhang
- Jing Sang
- Feifei Xu (ORCID: https://orcid.org/0000-0003-1946-1520)
- HuaNan Chen
- Meixiang Wang
- Ruiyang Ge
- Xin Ye
- Qi Xie
- Zhigang Wei
- Ji Ma
- Fu Wen
Institutions
- Weifang Medical University (CN)
- Shandong University (CN)
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
- Shandong Tumor Hospital (CN)
- Shandong Xiehe University (CN)
- Affiliated Hospital of Taishan Medical University (CN)
- Shandong Provincial QianFoShan Hospital (CN)
- Taian City Central Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Cancer Immunology Immunotherapy
- Published
- 2026-02-19
- DOI
- https://doi.org/10.1007/s00262-026-04317-y
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00