A conceptual health economic modelling framework to assess the cost-effectiveness of molecular target–driven treatment regimens in oncology
A dynamic, weighted multi-site modelling framework represents a coherent and adaptable extension of current health-technology assessment-practice for tumour-agnostic therapies. By structuring evidence around molecular targets, the framework can improve transparency and robustness of cost-effectiveness estimates, thereby supporting more equitable and efficient reimbursement decisions in the context of precision oncology.
Authors
- Peter Lindgren (ORCID: https://orcid.org/0000-0001-5493-3402)
- Ebba Hallersjö Hult (ORCID: https://orcid.org/0009-0005-7247-9510)
- Oskar Frisell (ORCID: https://orcid.org/0009-0004-3890-1848)
- Katarina Steen Carlsson (ORCID: https://orcid.org/0000-0002-2325-5634)
- K. Tasken
- Gro Live Fagereng (ORCID: https://orcid.org/0000-0003-2600-6606)
- Eline Aas
- Pia Sofie Henkel
Institutions
- Oslo University Hospital (NO)
- Norwegian Institute of Public Health (NO)
- Stockholm School of Economics (SE)
- University of Oslo (NO)
- Swedish Institute for Health Economics (SE)
Publication Details
- Journal
- Acta Oncologica
- Published
- 2026-02-19
- DOI
- https://doi.org/10.2340/1651-226x.2026.45088
- Citations
- 1
- Primary Topic
- Health Systems, Economic Evaluations, Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 99.81
Funders
- European Commission