Protective role of Probiatop® in mitigating 5-fluorouracil-induced intestinal mucositis in mice

Collectively, these findings demonstrate that Probiatop® exerts protective effects against 5-FU-induced intestinal mucositis, likely through coordinated modulation of epithelial barrier function, inflammatory responses, and microbial metabolic activity.

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Publication Details

Journal
Anaerobe
Published
2026-02-19
DOI
https://doi.org/10.1016/j.anaerobe.2026.103034
Primary Topic
Oral health in cancer treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Protective role of Probiatop® in mitigating 5-fluorouracil-induced intestinal mucositis in mice

Kátia Duarte Vital, Cardoso Vn, Fernanda Costa Souza, Jacques R. Nicoli et al.
Anaerobe
Oral health in cancer treatment
article

Protective role of Probiatop® in mitigating 5-fluorouracil-induced intestinal mucositis in mice

Kátia Duarte Vital, Cardoso Vn, Fernanda Costa Souza, Jacques R. Nicoli, L. M. B. Campos, Jamil Oliveira, Flaviano Santos Martins, Enio Ferreira, Bruno Gallotti, Ana P. Gomes, Luís C.L. De Jesus, Vasco Azevedo, Samantha.R.O. Machado, Simone.O.A. Fernandes
article en

Abstract

Collectively, these findings demonstrate that Probiatop® exerts protective effects against 5-FU-induced intestinal mucositis, likely through coordinated modulation of epithelial barrier function, inflammatory responses, and microbial metabolic activity.

AnaerobeVol. 97
Universidade Federal de Minas Gerais (BR)
Good health and well-being
Openalex Percentile: Top 49%
Oral health in cancer treatment
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