Decline of phosphatidylethanol (B‐PEth) during abstinence in patients with alcohol use disorder undergoing withdrawal treatment, and the correlation of B‐PEth with self‐reported alcohol intake

Elimination of phosphatidylethanol in blood (B-Peth) follows first-order kinetics, with homologue 16:0/18:1 exhibiting a longer half-life than 16:0/18:2. The rate of decline is influenced by the week of alcohol abstinence and B-PEth levels are detectable even in the fourth week of abstinence. The strongest correlation between B-PEth and self-reported alcohol consumption is at two weeks prior to abstinence.

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Publication Details

Journal
Addiction
Published
2026-02-19
DOI
https://doi.org/10.1111/add.70359
Primary Topic
Alcohol Consumption and Health Effects
Type
article
Field-Weighted Citation Impact
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article

Decline of phosphatidylethanol (B‐PEth) during abstinence in patients with alcohol use disorder undergoing withdrawal treatment, and the correlation of B‐PEth with self‐reported alcohol intake

Lisa Walther, Andrea de Bejczy, Cecilia Nilsson‐Wallmark, Anders Isaksson et al.
Addiction
Alcohol Consumption and Health Effects
article

Decline of phosphatidylethanol (B‐PEth) during abstinence in patients with alcohol use disorder undergoing withdrawal treatment, and the correlation of B‐PEth with self‐reported alcohol intake

Lisa Walther, Andrea de Bejczy, Cecilia Nilsson‐Wallmark, Anders Isaksson, Barbro Askerup
article en

Abstract

Elimination of phosphatidylethanol in blood (B-Peth) follows first-order kinetics, with homologue 16:0/18:1 exhibiting a longer half-life than 16:0/18:2. The rate of decline is influenced by the week of alcohol abstinence and B-PEth levels are detectable even in the fourth week of abstinence. The strongest correlation between B-PEth and self-reported alcohol consumption is at two weeks prior to abstinence.

Addiction
Lund University (SE), Sahlgrenska University Hospital (SE), Skåne University Hospital (SE), University of Gothenburg (SE)
Good health and well-being
Openalex Percentile: Top 51%
Alcohol Consumption and Health Effects
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Decline of phosphatidylethanol (B‐PEth) during abstinence in patients with alcohol use disorder undergoing withdrawal treatment, and the correlation of B‐PEth with self‐reported alcohol intake — Lisa Walther, Andrea de Bejczy, et al. · Addiction (2026) | TGRS Research Map | TGRS