Predictors of mortality in CNS tuberculosis: clinical and radiological parameters

Advanced age, elevated AST levels, increased CSF leukocyte count, cerebral ischemia, and extraparenchymal PCR positivity emerged as major predictors of mortality in CNS-TB. These factors may aid early risk stratification and treatment planning. Larger prospective studies are warranted to validate these findings.

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Publication Details

Journal
BMC Neurology
Published
2026-02-19
DOI
https://doi.org/10.1186/s12883-026-04656-4
Primary Topic
Infectious Diseases and Tuberculosis
Type
article
Field-Weighted Citation Impact
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article

Predictors of mortality in CNS tuberculosis: clinical and radiological parameters

Zeynep Yamazhan, Emre Kumral, Mesut Dorukoğlu
BMC Neurology
Infectious Diseases and Tuberculosis
article

Predictors of mortality in CNS tuberculosis: clinical and radiological parameters

Zeynep Yamazhan, Emre Kumral, Mesut Dorukoğlu
article en

Abstract

Advanced age, elevated AST levels, increased CSF leukocyte count, cerebral ischemia, and extraparenchymal PCR positivity emerged as major predictors of mortality in CNS-TB. These factors may aid early risk stratification and treatment planning. Larger prospective studies are warranted to validate these findings.

BMC NeurologyVol. 26(1)
Ege University (TR)
Good health and well-being
Openalex Percentile: Top 50%
Infectious Diseases and Tuberculosis
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Predictors of mortality in CNS tuberculosis: clinical and radiological parameters — Zeynep Yamazhan, Emre Kumral, et al. · BMC Neurology (2026) | TGRS Research Map | TGRS