Single-cell and spatial transcriptome analyses reveal tumor immunometabolism in lymph node metastasis of lung cancer

This study delineated transcriptional differences between primary tumors and MetLNs in lung cancer, thereby providing a foundation for further exploration of LN metastasis.

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Publication Details

Journal
Cancer Biology and Medicine
Published
2026-02-19
DOI
https://doi.org/10.20892/j.issn.2095-3941.2025.0587
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
0.00

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article

Single-cell and spatial transcriptome analyses reveal tumor immunometabolism in lymph node metastasis of lung cancer

Yushen Li, H. Chen, Xi Zhang, Wangyang Zhu et al.
Cancer Biology and Medicine
Single-cell and spatial transcriptomics
article

Single-cell and spatial transcriptome analyses reveal tumor immunometabolism in lymph node metastasis of lung cancer

Yushen Li, H. Chen, Xi Zhang, Wangyang Zhu, Chaoqiang Deng, Fangqiu Fu, Yuan Li, Yang Zhang, Yawei Zhang, Hong Hu, Jiaqing Xiang, Yihua Sun, Ting Ye
article en

Abstract

This study delineated transcriptional differences between primary tumors and MetLNs in lung cancer, thereby providing a foundation for further exploration of LN metastasis.

Cancer Biology and Medicine
Shanghai Medical College of Fudan University (CN), Fudan University (CN), Fudan University Shanghai Cancer Center (CN), Shanghai Institute of Materia Medica (CN)
Shanghai Municipal Health Commission, National Natural Science Foundation of China, Chinese Academy of Sciences
No poverty
Openalex Percentile: Top 50%
Single-cell and spatial transcriptomics
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