Investigating The Molecular Mechanism Of Icariin In Inhibiting Liver Cirrhosis Carcinogenesis By Regulating MiR-145 Based On The ROS-NLRP3 Pathway
Icariin effectively inhibits cirrhosis-associated carcinogenesis by suppressing the ROS-NLRP3 pathway and upregulating miR-145, providing a theoretical basis for the prevention and treatment of cirrhosis and hepatocellular carcinoma.
Authors
- Ting Cao (ORCID: https://orcid.org/0000-0001-9192-6981)
- Guang Li
- Yuyi Wang (ORCID: https://orcid.org/0000-0001-7273-9873)
- Wenjuan Wang (ORCID: https://orcid.org/0000-0001-9180-2823)
- Xiangda Meng
- Liping Cong
- Jing Zhang
- Chao Wu
- Shimin Wang
- Hongting Sui
Institutions
- Qiqihar University (CN)
- Mudanjiang Medical University (CN)
- Qiqihar Institute of Engineering (CN)
- Qiqihar Medical University (CN)
Publication Details
- Journal
- Pakistan Journal of Pharmaceutical Sciences
- Published
- 2026-02-01
- DOI
- https://doi.org/10.36721/pjps.2026.39.4.reg.15414.1
- Primary Topic
- Medicinal Plant Pharmacodynamics Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00