Methicillin-resistant Staphylococcus lugdunensis in a neonatal intensive care unit: diagnostic challenges and emergence of multidrug-resistance

We report a case of MRSL in an extremely premature neonate, which was the index patient in a neonatal intensive care unit outbreak, and highlight the diagnostic challenges faced in detection, screening and AST. Furthermore, we report the unusual antimicrobial susceptibility profile of this MRSL strain, caused by a multidrug-resistance plasmid with potential for transmission among staphylococci.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-02-19
DOI
https://doi.org/10.3389/fmed.2026.1765608
Primary Topic
Antimicrobial Resistance in Staphylococcus
Type
article
Field-Weighted Citation Impact
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article

Methicillin-resistant Staphylococcus lugdunensis in a neonatal intensive care unit: diagnostic challenges and emergence of multidrug-resistance

Torunn Gresdal Rønning, Siren Rettedal, H Enger, Heidi Syre et al.
Frontiers in Medicine
Antimicrobial Resistance in Staphylococcus
article

Methicillin-resistant Staphylococcus lugdunensis in a neonatal intensive care unit: diagnostic challenges and emergence of multidrug-resistance

Torunn Gresdal Rønning, Siren Rettedal, H Enger, Heidi Syre, Anlaug Vatne, Iren H. Löhr, Christina Gabrielsen Ås, Marianne Hille Smith, Jon Sundal
article en

Abstract

We report a case of MRSL in an extremely premature neonate, which was the index patient in a neonatal intensive care unit outbreak, and highlight the diagnostic challenges faced in detection, screening and AST. Furthermore, we report the unusual antimicrobial susceptibility profile of this MRSL strain, caused by a multidrug-resistance plasmid with potential for transmission among staphylococci.

Frontiers in MedicineVol. 13
Norwegian University of Science and Technology (NO), Stavanger University Hospital (NO), St Olav's University Hospital (NO), University of Bergen (NO), University of Stavanger (NO)
Openalex Percentile: Top 50%
Antimicrobial Resistance in Staphylococcus
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