Formulation and Application of a Human Insulin-Like Growth Factor 1-Loaded Transfersomal System to Enhance Skin Wound Healing in Diabetic Rat Models
Overall, this study demonstrated that hIGF-1 released from TF/hIGF-1 in a controlled manner could effectively promote re-epithelialization and granulation tissue formation in diabetic wounds of animal models compared to controls. These findings suggest a promising and effective approach for potential use in treating diabetic wounds.
Authors
- Parto Nasri (ORCID: https://orcid.org/0000-0002-9596-8860)
- Fahimeh Nojoki
- Amin Derakhshan (ORCID: https://orcid.org/0000-0002-1078-6516)
- Mahboobeh Forouzanfar
- Mohammad Hossein Nasr-Esfahani
- Kianoush Dormiani
- Sanaz Sedghi Esfahani
Institutions
- Isfahan University of Medical Sciences (IR)
- Royan Institute (IR)
- University of Tehran (IR)
- Academic Center for Education, Culture and Research (IR)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2026-02-01
- DOI
- https://doi.org/10.2147/ijn.s564241
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Royan Institute