Oncogenic LPCAT1 Accelerates Intrahepatic Cholangiocarcinoma Development Through PI3K/Akt Signaling‐Dependent Cell Cycle Regulation
LPCAT1 upregulates cell cycle proteins through activation of the PI3K/AKT signaling pathway, thereby promoting cellular proliferation and accelerating ICC progression.
Authors
- Yongjie Zhou
- Qing Xu
- Menglin Chen
- D. Zheng
- Enlai Jiang
- Yuwei Chen
Institutions
- Army Medical University (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- College of Contract Management (GB)
- Xinqiao Hospital (CN)
Publication Details
- Journal
- Journal of Gastroenterology and Hepatology
- Published
- 2026-02-19
- DOI
- https://doi.org/10.1111/jgh.70291
- Primary Topic
- Protein Kinase Regulation and GTPase Signaling
- Type
- article
- Field-Weighted Citation Impact
- 0.00