Successful Application of the Mast Cell Activation Test in Immediate Hypersensitivity to Amoxicillin
Under optimized conditions, MAT using dMCs and different AX determinants reached 75% sensitivity and 100% specificity. The complementary use of free AX and dendrimeric conjugates expands detection across heterogeneous IgE reactivity profiles from AX-allergic patients, reinforcing the diagnostic value of advanced cellular models and engineered allergens.
Authors
- Carlos J. Aranda (ORCID: https://orcid.org/0000-0001-6224-9352)
- Clara Lebrón‐Martín (ORCID: https://orcid.org/0000-0003-1694-7269)
- Amene Tesfaye Ayane (ORCID: https://orcid.org/0000-0003-0482-8895)
- María I. Montañez (ORCID: https://orcid.org/0000-0001-6641-5979)
- José Antonio Céspedes (ORCID: https://orcid.org/0000-0002-3318-3689)
- Adriana Ariza
- Pablo Torres
- M. J. Torres
- María Salas
- Gádor Bogas
- Cristobalina Mayorga
- Lucía Vallecillos‐Azor
Institutions
- Hospital Regional Universitario de Málaga (ES)
- Instituto de Investigación Biomédica de Málaga (ES)
- Universidad de Málaga (ES)
Publication Details
- Journal
- Allergy
- Published
- 2026-02-19
- DOI
- https://doi.org/10.1111/all.70267
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universidad de Málaga
- European Commission
- Ministerio de Ciencia e Innovación
- Junta de Andalucía
- HORIZON EUROPE Framework Programme
- Instituto de Salud Carlos III
- Agencia Estatal de Investigación
- European Social Fund
- HORIZON EUROPE Marie Sklodowska-Curie Actions