Identification of Novel Trypanosoma cruzi Cysteine Protease Inhibitors via Ligand-Based Virtual Screening of FDA-Approved Drugs with Trypanocidal Activity

These results encourage the development of new and more potent anti-<i>Trypanosoma cruzi</i> agents using FDA-approved drugs as scaffolds.

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Publication Details

Journal
Diseases
Published
2026-02-19
DOI
https://doi.org/10.3390/diseases14020079
Primary Topic
Trypanosoma species research and implications
Type
article
Field-Weighted Citation Impact
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article

Identification of Novel Trypanosoma cruzi Cysteine Protease Inhibitors via Ligand-Based Virtual Screening of FDA-Approved Drugs with Trypanocidal Activity

Ana Verónica Martínez-Vázquez, C Aguirre-Alvarado, Lenci K. Vázquez‐Jiménez, Rogelio Gómez-Escobedo et al.
Diseases
Trypanosoma species research and implications
article

Identification of Novel Trypanosoma cruzi Cysteine Protease Inhibitors via Ligand-Based Virtual Screening of FDA-Approved Drugs with Trypanocidal Activity

Ana Verónica Martínez-Vázquez, C Aguirre-Alvarado, Lenci K. Vázquez‐Jiménez, Rogelio Gómez-Escobedo, Eyra Ortíz-Pérez, Veronica Alcantara-Farfán, G Gibrán Rivera, Alonzo González-González, L. Rodríguez-Páez, Benjamín Nogueda‐Torres, Adriana Moreno-Rodriguez, Timoteo Delgado-Maldonado, Joaquín Cordero-Martínez
article en

Abstract

These results encourage the development of new and more potent anti-<i>Trypanosoma cruzi</i> agents using FDA-approved drugs as scaffolds.

DiseasesVol. 14(2)
Secretaría de Ciencia Tecnología e Innovación (MX), Instituto Politécnico Nacional (MX), Benito Juárez Autonomous University of Oaxaca (MX)
Good health and well-being
Openalex Percentile: Top 50%
Trypanosoma species research and implications
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