Development of a risk assessment model for the recurrence of high-grade squamous intraepithelial lesions and differentiated vulvar intraepithelial neoplasia in Chinese cohort

A prediction model including age, smoking history, immunosuppression, HPV16 infection, and histopathology exhibits good predictive performance for post-treatment recurrence of HSIL and dVIN. Our model can help clinicians assess recurrence risk, providing guidance for clinical consultations and enabling targeted follow-up and treatment plans for individuals at high risk.

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Publication Details

Journal
Discover Oncology
Published
2026-02-19
DOI
https://doi.org/10.1007/s12672-026-04714-w
Primary Topic
Cervical Cancer and HPV Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Development of a risk assessment model for the recurrence of high-grade squamous intraepithelial lesions and differentiated vulvar intraepithelial neoplasia in Chinese cohort

X. Zhang, Le Yu, Chenmin Zheng, Xuanxuan Hong et al.
Discover Oncology
Cervical Cancer and HPV Research
article

Development of a risk assessment model for the recurrence of high-grade squamous intraepithelial lesions and differentiated vulvar intraepithelial neoplasia in Chinese cohort

X. Zhang, Le Yu, Chenmin Zheng, Xuanxuan Hong, Xi Ye, Fei Wang, Liehong Wang
article en

Abstract

A prediction model including age, smoking history, immunosuppression, HPV16 infection, and histopathology exhibits good predictive performance for post-treatment recurrence of HSIL and dVIN. Our model can help clinicians assess recurrence risk, providing guidance for clinical consultations and enabling targeted follow-up and treatment plans for individuals at high risk.

Discover OncologyVol. 17(1)
Qinghai University (CN), Qinghai University Affiliated Hospital (CN), Qinghai Red Cross Hospital (CN), Anhui Mental Health Center (CN)
Good health and well-being
Openalex Percentile: Top 50%
Cervical Cancer and HPV Research
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Development of a risk assessment model for the recurrence of high-grade squamous intraepithelial lesions and differentiated vulvar intraepithelial neoplasia in Chinese cohort — X. Zhang, Le Yu, et al. · Discover Oncology (2026) | TGRS Research Map | TGRS