Presence of Dengue Virus NS1 antigen and IgM and IgG antibodies in asymptomatic individuals in Ecuadorian Amazonia - a descriptive repeated cross-sectional community-based survey
Dengue virus transmission in the Putumayo Amazonia region extends beyond hospital-detected cases into river-access-only communities. The inverted ratio of acute-to-past infection between urban and riverine settlements suggests source-sink dynamics with ongoing viral movement along fluvial networks. As malaria elimination progresses, integrated arboviral surveillance incorporating community-based RDT screening and field laboratories is essential to detect emerging viral transmission invisible to facility-based systems.
Authors
- Thomas Hänscheid (ORCID: https://orcid.org/0000-0001-6353-9132)
- Jacob van der Ende
- Martin P. Grobusch
- Henk Schallig
- M.Vanessa Davila
Institutions
- University of Lisbon (PT)
- University of Cape Town (ZA)
- Centre de Recherche Médicales de Lambaréné (GA)
- Hospital de Egas Moniz (PT)
- German Center for Infection Research (DE)
- Amsterdam Institute for Global Health and Development (NL)
- Amsterdam University Medical Centers (NL)
- Fundación Para La Investigación Y Gestión En Servicios de Salud (EC)
- Sierra Leone Agricultural Research Institute (SL)
- Universidad San Francisco de Quito (EC)
- Universidade Nova de Lisboa (PT)
- University of Amsterdam (NL)
- University of California, Berkeley (US)
Publication Details
- Journal
- New Microbes and New Infections
- Published
- 2026-02-19
- DOI
- https://doi.org/10.1016/j.nmni.2026.101728
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universiteit van Amsterdam
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases