The overlooked burden: anti-seizure medications, laxatives, and antipsychotics prescribed in primary care for people with intellectual disability

Nearly half of PwID on ASMs are prescribed laxatives, and over a third of them were also found to be taking antipsychotics. Given the significant links among epilepsy, constipation, and antipsychotic use to premature mortality in PwID, it is imperative to consider these factors collectively rather than individually.

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Publication Details

Journal
Frontiers in Psychiatry
Published
2026-02-19
DOI
https://doi.org/10.3389/fpsyt.2026.1714524
Primary Topic
Down syndrome and intellectual disability research
Type
article
Field-Weighted Citation Impact
0.00
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article

The overlooked burden: anti-seizure medications, laxatives, and antipsychotics prescribed in primary care for people with intellectual disability

Richard Laugharne, Rohit Shankar, Ian Wilson
Frontiers in Psychiatry
Down syndrome and intellectual disability research
article

The overlooked burden: anti-seizure medications, laxatives, and antipsychotics prescribed in primary care for people with intellectual disability

Richard Laugharne, Rohit Shankar, Ian Wilson
article en

Abstract

Nearly half of PwID on ASMs are prescribed laxatives, and over a third of them were also found to be taking antipsychotics. Given the significant links among epilepsy, constipation, and antipsychotic use to premature mortality in PwID, it is imperative to consider these factors collectively rather than individually.

Frontiers in PsychiatryVol. 17
Royal Cornwall Hospital Trust (GB), Western Isles Hospital (GB), Cornwall Partnership NHS Foundation Trust (GB), Peninsula College of Medicine and Dentistry (GB)
Openalex Percentile: Top 53%
Down syndrome and intellectual disability research
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