Bergapten Alleviates Parkinson's Disease-Like Behaviors In Mice By Inhibiting Astrocyte Inflammatory Activation And Endoplasmic Reticulum Stress Through The Regulation Of The LCN2/JAK2/STAT3 Pathway
These findings suggest that BeG exerts neuroprotective effects in PD by inhibiting the LCN2/JAK2/STAT3 signaling pathway, thereby effectively inhibiting astrocyte activation-mediated neuroinflammation and ERS.
Authors
- Jiahui Liu (ORCID: https://orcid.org/0000-0002-9522-6875)
- Rong Tang (ORCID: https://orcid.org/0000-0001-7142-6250)
- Jiaxin Li
Institutions
- Baotou Central Hospital (CN)
- Baotou Medical College (CN)
Publication Details
- Journal
- Pakistan Journal of Pharmaceutical Sciences
- Published
- 2026-02-01
- DOI
- https://doi.org/10.36721/pjps.2026.39.4.reg.15008.1
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00