Children’s gut microbiota predicts the efficacy of obesity treatment

Higher baseline gut microbiota diversity and specific microbial signatures, particularly <i>Faecalibacterium</i> abundance, predicted better outcomes in childhood obesity interventions. These findings support the potential use of microbiota profiling to guide personalised treatment strategies. Further research is needed to optimise interventions.<b>Trial registration:</b> clinicaltrials.gov NCT03749291.

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Publication Details

Journal
Gut Microbes
Published
2026-02-19
DOI
https://doi.org/10.1080/19490976.2026.2631824
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

Children’s gut microbiota predicts the efficacy of obesity treatment

Albert Feliu, Gemma Castillejo, Joaquín Escribano, R. Closa-Monasterolo et al.
Gut Microbes
Gut microbiota and health
article

Children’s gut microbiota predicts the efficacy of obesity treatment

Albert Feliu, Gemma Castillejo, Joaquín Escribano, R. Closa-Monasterolo, Mariona Gispert-Llauradó, Natalia Ferré, Verónica Luque, Judit Muñoz-Hernando
article en

Abstract

Higher baseline gut microbiota diversity and specific microbial signatures, particularly <i>Faecalibacterium</i> abundance, predicted better outcomes in childhood obesity interventions. These findings support the potential use of microbiota profiling to guide personalised treatment strategies. Further research is needed to optimise interventions.<b>Trial registration:</b> clinicaltrials.gov NCT03749291.

Gut MicrobesVol. 18(1)
Universidade Católica de Pernambuco (BR), Hospital Universitari Sant Joan de Reus (ES), Universitat Rovira i Virgili (ES)
Zero hunger
Openalex Percentile: Top 50%
Gut microbiota and health
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