Can cadmium toxicity be a driving force for iron deficiency anemia – a systematic review and meta-analysis

This is the first meta-analysis assessing the association between cadmium toxicity and iron deficiency. Our findings demonstrate that cadmium may be effective in triggering iron deficiency anemia and inflammation-induced anemia by impairing iron metabolism. However, it should be noted that more detailed studies are needed to clarify these effects of cadmium.

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Publication Details

Journal
Reviews on Environmental Health
Published
2026-02-19
DOI
https://doi.org/10.1515/reveh-2025-0080
Primary Topic
Heavy Metal Exposure and Toxicity
Type
article
Field-Weighted Citation Impact
0.00
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article

Can cadmium toxicity be a driving force for iron deficiency anemia – a systematic review and meta-analysis

Irem Akin, Nuray Yazıhan
Reviews on Environmental Health
Heavy Metal Exposure and Toxicity
article

Can cadmium toxicity be a driving force for iron deficiency anemia – a systematic review and meta-analysis

Irem Akin, Nuray Yazıhan
article en

Abstract

This is the first meta-analysis assessing the association between cadmium toxicity and iron deficiency. Our findings demonstrate that cadmium may be effective in triggering iron deficiency anemia and inflammation-induced anemia by impairing iron metabolism. However, it should be noted that more detailed studies are needed to clarify these effects of cadmium.

Reviews on Environmental Health
Ankara University (TR)
Zero hunger
Openalex Percentile: Top 54%
Heavy Metal Exposure and Toxicity
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