Association Between Serum Pyridoxal 5′‐Phosphate and Frailty Risk in Community‐Dwelling Older Japanese Adults

The relationship between PLP levels and pre-frailty/frailty was found to be non-linear. The lowest prevalence was observed in Q2, whereas both low and high PLP levels were associated with increased ORs of pre-frailty/frailty. Further prospective studies are needed to clarify the causal relationship in older Japanese adults.

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Publication Details

Journal
Geriatrics and gerontology international/Geriatrics & gerontology international
Published
2026-02-01
DOI
https://doi.org/10.1111/ggi.70412
Primary Topic
Folate and B Vitamins Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Association Between Serum Pyridoxal 5′‐Phosphate and Frailty Risk in Community‐Dwelling Older Japanese Adults

Hiroaki Kanouchi, Akiko Kuwabara, Kaori Kaimoto, Toshihiro Takenaka et al.
Geriatrics and gerontology international/Geriatrics & gerontology international
Folate and B Vitamins Research
article

Association Between Serum Pyridoxal 5′‐Phosphate and Frailty Risk in Community‐Dwelling Older Japanese Adults

Hiroaki Kanouchi, Akiko Kuwabara, Kaori Kaimoto, Toshihiro Takenaka, Sachiko Aburada, Keishi Miyata, Kayoko Imamura, Takuro Kubozono, Hyuma Makizako, Hisami Manabe, Maika Ohta
article en

Abstract

The relationship between PLP levels and pre-frailty/frailty was found to be non-linear. The lowest prevalence was observed in Q2, whereas both low and high PLP levels were associated with increased ORs of pre-frailty/frailty. Further prospective studies are needed to clarify the causal relationship in older Japanese adults.

Geriatrics and gerontology international/Geriatrics & gerontology internationalVol. 26(2)
Kagoshima University (JP), Tartu University Hospital (EE), Kagoshima Women's Junior College (JP), Kagoshima Medical Corporation Association Nursing College (JP), Kagoshima Immaculate Heart University (JP), Osaka Metropolitan University (JP)
Openalex Percentile: Top 52%
Folate and B Vitamins Research
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Association Between Serum Pyridoxal 5′‐Phosphate and Frailty Risk in Community‐Dwelling Older Japanese Adults — Hiroaki Kanouchi, Akiko Kuwabara, et al. · Geriatrics and gerontology international/Geriatrics & gerontology international (2026) | TGRS Research Map | TGRS