Association of serum albumin levels with multidomain functional impairment (motor, balance, ADL, and cognitive impairment) in Chinese post-stroke patients: a multicenter cross-sectional study
ALB levels are independently and dose-dependently associated with motor, ADL, balance, and cognitive function in post-stroke patients. Compared to lower quartiles, patients with ALB ≥42.8 g/L (highest quartile) exhibit superior functional outcomes. A sex-specific pattern is observed solely in motor function, where the correlation is more pronounced in females. ALB may serve as a biological indicator for risk stratification during stroke rehabilitation.
Authors
- Shuyang Zhang (ORCID: https://orcid.org/0009-0009-9758-5861)
- Jiali Lin (ORCID: https://orcid.org/0000-0001-6939-0076)
- Xinyu Zhao (ORCID: https://orcid.org/0000-0002-5128-4424)
- Ranran Bi
- Yifang Lin
- Yansheng Lin
- Jie Zhu
- Jie Jia
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
- Fujian Medical University (CN)
- Fudan University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
- National Clinical Research (US)
- Shanghai East Hospital (CN)
- Huashan Hospital (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2026-02-19
- DOI
- https://doi.org/10.3389/fneur.2026.1763978
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- General Hospital of People’s Liberation Army