Understanding the developmental trajectory of behavioral problems and subcortical structure morphometry in healthy children at 6 years old and long-term impact of early nutrition: the COGNIS study

These findings suggest that non-linear behavioral growth models more effectively reflect brain-behavior associations. Futhermore, subcortical brain morphometry, particularly of the hippocampus, may be shaped by behavioral patterns during critical developmental windows-most notably around 2.5 years of age.

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Publication Details

Journal
Child and Adolescent Psychiatry and Mental Health
Published
2026-02-19
DOI
https://doi.org/10.1186/s13034-026-01030-7
Primary Topic
Infant Development and Preterm Care
Type
article
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article

Understanding the developmental trajectory of behavioral problems and subcortical structure morphometry in healthy children at 6 years old and long-term impact of early nutrition: the COGNIS study

Elvira Catena-Verdejo, Ana Nieto-Ruíz, C Campoy, Florian Herrmann et al.
Child and Adolescent Psychiatry and Mental Health
Infant Development and Preterm Care
article

Understanding the developmental trajectory of behavioral problems and subcortical structure morphometry in healthy children at 6 years old and long-term impact of early nutrition: the COGNIS study

Elvira Catena-Verdejo, Ana Nieto-Ruíz, C Campoy, Florian Herrmann, Andrés Catena, José Antonio García-Santos, Roser De-Castellar, Mª Teresa Pérez-Hernández
article en

Abstract

These findings suggest that non-linear behavioral growth models more effectively reflect brain-behavior associations. Futhermore, subcortical brain morphometry, particularly of the hippocampus, may be shaped by behavioral patterns during critical developmental windows-most notably around 2.5 years of age.

Child and Adolescent Psychiatry and Mental HealthVol. 20(1)
Universidad de Granada (ES), Instituto de Salud Carlos III (ES), Instituto de Investigación Biosanitaria de Granada (ES), Ordesa (Spain) (ES), Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES)
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Understanding the developmental trajectory of behavioral problems and subcortical structure morphometry in healthy children at 6 years old and long-term impact of early nutrition: the COGNIS study — Elvira Catena-Verdejo, Ana Nieto-Ruíz, et al. · Child and Adolescent Psychiatry and Mental Health (2026) | TGRS Research Map | TGRS