Hemodynamic effects of red blood cell transfusion in patients with hemato-oncologic diseases
RBC transfusion in patients with hemato-oncologic diseases resulted in significant increases in central and peripheral blood pressures and a reduction in heart rate in our pilot study. Trends toward improved blood rheology and vascular function were observed, though not statistically significant. While these immediate hemodynamic effects appear beneficial, further research is needed to determine long-term outcomes, especially for patients requiring frequent transfusions.
Authors
- R. D. Hofheinz
- Sabine Käyser (ORCID: https://orcid.org/0000-0003-3796-8843)
- Anna Hohneck (ORCID: https://orcid.org/0000-0002-7629-2770)
- Babak Yazdani (ORCID: https://orcid.org/0000-0001-9222-8958)
- Mohammed L. Abba (ORCID: https://orcid.org/0000-0002-1211-0843)
- Goekhan Yuecel
- D Duerschmied
- Nikoletta Schneider
- Gerhard Schumacher
- Mark Schulz
Institutions
- Heidelberg University (DE)
- German Red Cross (DE)
- University Hospital Heidelberg (DE)
- IQE (United Kingdom) (GB)
- German Centre for Cardiovascular Research (DE)
- University Medical Centre Mannheim (DE)
- German Center for Diabetes Research (DE)
- Harz University of Applied Sciences (DE)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2026-02-19
- DOI
- https://doi.org/10.3389/fmed.2026.1711829
- Primary Topic
- Blood transfusion and management
- Type
- article
- Field-Weighted Citation Impact
- 0.00