Late Onset of Congenital TTP: Case Presentation and Review of the Literature

The present case of cTTP is notable for its late onset at first presentation, with unusual severe renal impairment. Rapid diagnosis and timely initiation of treatment are critical. Differential diagnoses such as malignant hypertension, sepsis, and autoimmune diseases like systemic lupus erythematosus must be excluded.

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Publication Details

Journal
Clinical Medicine Insights Case Reports
Published
2026-02-18
DOI
https://doi.org/10.1177/11795476261421638
Primary Topic
Complement system in diseases
Type
article
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article

Late Onset of Congenital TTP: Case Presentation and Review of the Literature

Ulf Janssen, Athanasios Chatzisfetkos, Carsten Bergmann
Clinical Medicine Insights Case Reports
Complement system in diseases
article

Late Onset of Congenital TTP: Case Presentation and Review of the Literature

Ulf Janssen, Athanasios Chatzisfetkos, Carsten Bergmann
article en

Abstract

The present case of cTTP is notable for its late onset at first presentation, with unusual severe renal impairment. Rapid diagnosis and timely initiation of treatment are critical. Differential diagnoses such as malignant hypertension, sepsis, and autoimmune diseases like systemic lupus erythematosus must be excluded.

Clinical Medicine Insights Case ReportsVol. 19
Kliniken Maria Hilf (DE)
Gender equality
Openalex Percentile: Top 49%
Complement system in diseases
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Late Onset of Congenital TTP: Case Presentation and Review of the Literature — Ulf Janssen, Athanasios Chatzisfetkos, et al. · Clinical Medicine Insights Case Reports (2026) | TGRS Research Map | TGRS