Alveolar echinococcosis drives functional reprogramming of hepatic CD8+ T cells
AE infection drives a transition from acute inflammation to chronic immune regulation through extensive lineage diversification and functional reprogramming of CD8<sup>+</sup> T cells. Spatially organized DC-T-cell interactions likely contribute to maintaining a regulated yet immunologically active microenvironment, providing insights for targeting chronic-stage immune responses in AE.
Authors
- Jing Tang (ORCID: https://orcid.org/0000-0002-8745-9177)
- Siyu Hou (ORCID: https://orcid.org/0000-0001-8341-6607)
- Yazhou Zhu
- Bingshuo Qian
- Zihua Li
- Wei Zhao
- Xiaoli Qin
- Tao Li
- Yinqi Zhao
- Peijiao Wu
- Yan Huo
Institutions
- Ningxia Medical University (CN)
- Ningxia Medical University General Hospital (CN)
- Ningxia Center for Diseases Prevention and Control (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2026-02-19
- DOI
- https://doi.org/10.3389/fcimb.2026.1747682
- Primary Topic
- Parasitic infections in humans and animals
- Type
- article
- Field-Weighted Citation Impact
- 0.00