Integrating pleural PD-1+CD8+ T cell as a complement variable into LENT score to assess patients with lung adenocarcinoma complicated with MPE
The combination of pleural PD-1<sup>+</sup>CD8<sup>+</sup> T cells with the LENT score offers a more accurate prognostic tool for survival prediction in NSCLC patients with MPE. Our findings suggest that the Immuno-LENT score could guide clinical management and inform therapeutic decisions for these patients, improving patient outcomes by tailoring interventions based on a more comprehensive biomarker profile.
Authors
- Yaoxin Zhang (ORCID: https://orcid.org/0000-0001-5540-4959)
- Weizhen Jiang
- Chen Ce
- Leilei Lv
- Qiuxia Qu
Institutions
- Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-19
- DOI
- https://doi.org/10.3389/fimmu.2026.1630590
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Suzhou City
- National Natural Science Foundation of China
- Soochow University