Elevated serum peroxiredoxin 1 is a biomarker of multiorgan failure in ARDS
Serum PRDX1 was significantly elevated in ARDS patients, particularly in those with multiorgan injury, and demonstrated potential as a prognostic biomarker, showing correlation with 28-day mortality. Its integration into the ARDS management framework holds significant potential for improving clinical outcomes.
Authors
- Lijun Zou
- Mao Jiang (ORCID: https://orcid.org/0000-0002-0621-1349)
- Hanwei Huang (ORCID: https://orcid.org/0000-0001-5238-8594)
- Yijun He (ORCID: https://orcid.org/0000-0003-1152-2907)
- Yi Liu (ORCID: https://orcid.org/0000-0002-1058-0382)
- Jie Meng
- Pan Yu
- Tingting Yao
- Xiaoyun Cheng
- Lingzhi Long
- Yan Zhang
- Xiangyu Zhang
- Guoliang Jiang
Institutions
- Central South University (CN)
- Yueyang Second People's Hospital (CN)
- Third Xiangya Hospital (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- BMJ Open Respiratory Research
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1136/bmjresp-2025-003687
- Primary Topic
- Redox biology and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China