Fecal short-chain fatty acids and serum metabolites: the impact of COVID-19 infection on dialysis patients

COVID-19 infection in dialysis patients is associated with marked depletion of fecal SCFAs and broad perturbations of systemic metabolism, with persistent amino-acid-centered alterations among patients who develop LC. These findings offer a novel metabolic framework supporting the implementation of prolonged follow-up strategies to monitor and ameliorate persistent sequelae in this high-risk population.

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Publication Details

Journal
Frontiers in Nutrition
Published
2026-02-19
DOI
https://doi.org/10.3389/fnut.2026.1772671
Primary Topic
Metabolomics and Mass Spectrometry Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Fecal short-chain fatty acids and serum metabolites: the impact of COVID-19 infection on dialysis patients

Yuwei Chen, Duo Yu, Changlin Li, Jiamin Duan et al.
Frontiers in Nutrition
Metabolomics and Mass Spectrometry Studies
article

Fecal short-chain fatty acids and serum metabolites: the impact of COVID-19 infection on dialysis patients

Yuwei Chen, Duo Yu, Changlin Li, Jiamin Duan, Yuting Li, Xiaomeng Lin, Qingli Yang, Jing Zhang, Xudong Cai
article en

Abstract

COVID-19 infection in dialysis patients is associated with marked depletion of fecal SCFAs and broad perturbations of systemic metabolism, with persistent amino-acid-centered alterations among patients who develop LC. These findings offer a novel metabolic framework supporting the implementation of prolonged follow-up strategies to monitor and ameliorate persistent sequelae in this high-risk population.

Frontiers in NutritionVol. 13
Zhejiang Chinese Medical University (CN)
National Natural Science Foundation of China, Zhejiang Traditional Chinese Medicine Administration, Natural Science Foundation of Zhejiang Province
Affordable and clean energy
Openalex Percentile: Top 50%
Metabolomics and Mass Spectrometry Studies
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