IgA/IgM Enriched Immunoglobulin Therapy for Recurrent Pulmonary Infections in a Patient With Partial IgA Deficiency and Lung Transplantation

A 57-year-old man with partial selective IgA deficiency (normal IgM, IgG, and IgG subclass levels; normal T and B lymphocyte counts; vaccine challenge not performed) underwent bilateral lung transplantation in March 2022 for progressive fibrosing interstitial lung disease, classified as probable hypersensitivity pneumonitis, without an identifiable cause.He had no prior history of immunosuppressive therapy.

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Publication Details

Journal
Transplant Infectious Disease
Published
2026-02-19
DOI
https://doi.org/10.1111/tid.70189
Primary Topic
Immunodeficiency and Autoimmune Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

IgA/IgM Enriched Immunoglobulin Therapy for Recurrent Pulmonary Infections in a Patient With Partial IgA Deficiency and Lung Transplantation

Lucas Arduin, Benjamin Coiffard, Nadim Cassir
Transplant Infectious Disease
Immunodeficiency and Autoimmune Disorders
article

IgA/IgM Enriched Immunoglobulin Therapy for Recurrent Pulmonary Infections in a Patient With Partial IgA Deficiency and Lung Transplantation

Lucas Arduin, Benjamin Coiffard, Nadim Cassir
article en

Abstract

A 57-year-old man with partial selective IgA deficiency (normal IgM, IgG, and IgG subclass levels; normal T and B lymphocyte counts; vaccine challenge not performed) underwent bilateral lung transplantation in March 2022 for progressive fibrosing interstitial lung disease, classified as probable hypersensitivity pneumonitis, without an identifiable cause.He had no prior history of immunosuppressive therapy.

Transplant Infectious Disease
Inserm (FR), Aix-Marseille Université (FR), Méditerranée Infection Foundation (FR), Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR), Hôpital Nord (FR)
Good health and well-being
Openalex Percentile: Top 49%
Immunodeficiency and Autoimmune Disorders
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