The high-sensitivity C-reactive protein-to-high-density lipoprotein cholesterol ratio as a novel composite biomarker for predicting 28-day all-cause mortality in sepsis: a retrospective cohort study

HCHR is independently associated with 28-day all-cause mortality in sepsis and demonstrates moderate discriminative performance. HCHR may serve as a useful adjunct biomarker to support early risk stratification in sepsis.