Efficacy and safety of camrelizumab-based regimens in advanced squamous cell carcinoma patients: a prospective multicenter study

Camrelizumab shows satisfactory efficacy and safety in advanced esophageal cancer patients, and the camrelizumab combination regimens seem to bring prolonged PFS than its monotherapy. The real-world design reflects routine clinical practice, supporting the generalizability of these findings. However, potential confounders may exist and the broad range of follow-up durations may contribute to variability in survival data. Therefore, our results should be interpreted cautiously.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2026-02-19
DOI
https://doi.org/10.3389/fphar.2026.1767096
Primary Topic
Esophageal Cancer Research and Treatment
Type
article
Field-Weighted Citation Impact
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article

Efficacy and safety of camrelizumab-based regimens in advanced squamous cell carcinoma patients: a prospective multicenter study

Wenxia Deng, G. Sun, Tai Ma, Xinglai Guo et al.
Frontiers in Pharmacology
Esophageal Cancer Research and Treatment
article

Efficacy and safety of camrelizumab-based regimens in advanced squamous cell carcinoma patients: a prospective multicenter study

Wenxia Deng, G. Sun, Tai Ma, Xinglai Guo, Wanren Peng, Hong Qian, Chenghui Li, Zhongxian Zheng, Dong Qian, Zhiyong Wei, Gang Wang, Shaojin Zhu, Xiangde Jiang, Zishu Wang, Dong Zhao, Liming Xia, Jie Wei, Weijia Jiang, Xinzhong Li, Genhe Wang, Yifu He
article en

Abstract

Camrelizumab shows satisfactory efficacy and safety in advanced esophageal cancer patients, and the camrelizumab combination regimens seem to bring prolonged PFS than its monotherapy. The real-world design reflects routine clinical practice, supporting the generalizability of these findings. However, potential confounders may exist and the broad range of follow-up durations may contribute to variability in survival data. Therefore, our results should be interpreted cautiously.

Frontiers in PharmacologyVol. 17
Wannan Medical College (CN), Anhui Medical University (CN), Anhui University of Traditional Chinese Medicine (CN), Huangshan University (CN), Chizhou University (CN), Huaibei Mining (China) (CN), Huaian First People’s Hospital (CN), The People's Hospital Tongling (CN), Bozhou People's Hospital (CN), Fuyang Maternity and Child Health Care Hospital (CN), Anhui Provincial Hospital (CN), Anqing City Hospital (CN), First Affiliated Hospital of Anhui Medical University (CN), First Affiliated Hospital of Bengbu Medical College (CN), Cixian People's Hospital (CN), Anyang Tumor Hospital (CN), First People's Hospital of Jingzhou (CN)
Good health and well-being
Openalex Percentile: Top 50%
Esophageal Cancer Research and Treatment
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