EPPT–CTG regeneration using rhFGF‐2/CO <sub>3</sub> Ap for Cemental Tear Defects: A case report

This case report describes a new treatment method for repairing bone loss around a tooth caused by a "cemental tear," a type of root surface damage that can lead to gum swelling and bone destruction. A 73-year-old male patient was treated with a combination of a growth factor (rhFGF-2), a synthetic bone substitute (CO<sub>3</sub>Ap), and a small piece of gum tissue (CTG) using a minimally invasive surgical technique that preserves the entire gum papilla. Over 12 months, the treatment resulted in significant healing of both bone and gum tissues without recession. This approach may offer a reliable option for saving teeth with similar severe bone defects.

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Publication Details

Journal
Clinical Advances in Periodontics
Published
2026-02-19
DOI
https://doi.org/10.1002/cap.70048
Primary Topic
Periodontal Regeneration and Treatments
Type
article
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article

EPPT–CTG regeneration using rhFGF‐2/CO 3 Ap for Cemental Tear Defects: A case report

Yukiko Nagatani, Takayoshi Nagahara, Keinoshin Wada, Noriyoshi Mizuno et al.
Clinical Advances in Periodontics
Periodontal Regeneration and Treatments
article

EPPT–CTG regeneration using rhFGF‐2/CO 3 Ap for Cemental Tear Defects: A case report

Yukiko Nagatani, Takayoshi Nagahara, Keinoshin Wada, Noriyoshi Mizuno, Kosuke Yamamoto, Tomoyuki Iwata, Masaru Shimizu
article en

Abstract

This case report describes a new treatment method for repairing bone loss around a tooth caused by a "cemental tear," a type of root surface damage that can lead to gum swelling and bone destruction. A 73-year-old male patient was treated with a combination of a growth factor (rhFGF-2), a synthetic bone substitute (CO<sub>3</sub>Ap), and a small piece of gum tissue (CTG) using a minimally invasive surgical technique that preserves the entire gum papilla. Over 12 months, the treatment resulted in significant healing of both bone and gum tissues without recession. This approach may offer a reliable option for saving teeth with similar severe bone defects.

Clinical Advances in Periodontics
Hiroshima University (JP), Yamamoto Hospital (JP), Fujimoto Dental and Oral Surgery Clinic (JP), Fukuyama Cardiovascular Hospital (JP)
Openalex Percentile: Top 48%
Periodontal Regeneration and Treatments
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EPPT–CTG regeneration using rhFGF‐2/CO <sub>3</sub> Ap for Cemental Tear Defects: A case report — Yukiko Nagatani, Takayoshi Nagahara, et al. · Clinical Advances in Periodontics (2026) | TGRS Research Map | TGRS