In-Depth Analysis of the Intravitreal Biocompatibility of Polyethylene Glycol of Different Molecular Weight in an In Vivo Porcine Model

The one-time intravitreal injection of PEG causes mild intravitreal inflammatory reactions, as evidenced in OCT by increased vitreous cells. However, retinal structure and function is not affected.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2026-02-19
DOI
https://doi.org/10.1167/iovs.67.2.37
Primary Topic
Retinal and Macular Surgery
Type
article
Field-Weighted Citation Impact
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article

In-Depth Analysis of the Intravitreal Biocompatibility of Polyethylene Glycol of Different Molecular Weight in an In Vivo Porcine Model

Jonathan Herth, Philipp Uhl, Gerd Uwe Auffarth, Alexander Studier‐Fischer et al.
Investigative Ophthalmology & Visual Science
Retinal and Macular Surgery
article

In-Depth Analysis of the Intravitreal Biocompatibility of Polyethylene Glycol of Different Molecular Weight in an In Vivo Porcine Model

Jonathan Herth, Philipp Uhl, Gerd Uwe Auffarth, Alexander Studier‐Fischer, Sabrina Wohlfart, Maximilian Hammer, Lea Skrzypczyk, Bryan Calder Ackermann, Ludwig Geisweid, Niklas Junker, Walter Mier, Victor A. Augustin
article en

Abstract

The one-time intravitreal injection of PEG causes mild intravitreal inflammatory reactions, as evidenced in OCT by increased vitreous cells. However, retinal structure and function is not affected.

Investigative Ophthalmology & Visual ScienceVol. 67(2)
Apple (Israel) (IL), Heidelberg University (DE), University Hospital Heidelberg (DE), University Medical Centre Mannheim (DE)
Openalex Percentile: Top 51%
Retinal and Macular Surgery
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