Benefit of adjuvant chemotherapy in patients with T1a-bN0, triple-negative breast cancer – A systematic review and meta-analysis

Chemotherapy was associated with higher survival in patients with T1bN0 TNBC, but not in patients with T1aN0 tumors. Overall, 5-year outcomes were high even without chemotherapy. These findings support current guideline recommendations.

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Publication Details

Journal
Critical Reviews in Oncology/Hematology
Published
2026-02-19
DOI
https://doi.org/10.1016/j.critrevonc.2026.105225
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Benefit of adjuvant chemotherapy in patients with T1a-bN0, triple-negative breast cancer – A systematic review and meta-analysis

Carsten Bogh Juhl, N. Kroman, Iben Kümler, Tove Holst Filtenborg Tvedskov et al.
Critical Reviews in Oncology/Hematology
Breast Cancer Treatment Studies
article

Benefit of adjuvant chemotherapy in patients with T1a-bN0, triple-negative breast cancer – A systematic review and meta-analysis

Carsten Bogh Juhl, N. Kroman, Iben Kümler, Tove Holst Filtenborg Tvedskov, Ann Søegaard Knoop, Dorte Lisbet Nielsen, Christina M.S. Hassing
article en

Abstract

Chemotherapy was associated with higher survival in patients with T1bN0 TNBC, but not in patients with T1aN0 tumors. Overall, 5-year outcomes were high even without chemotherapy. These findings support current guideline recommendations.

Critical Reviews in Oncology/HematologyVol. 221
Herlev Hospital (DK), Copenhagen University Hospital (DK), Gentofte Hospital (DK), Rigshospitalet (DK)
Gentofte Hospital, Helsefonden
Good health and well-being
Openalex Percentile: Top 49%
Breast Cancer Treatment Studies
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