Divergent roles of circMPP6 and its parental gene MPP6 in non-small cell lung cancer

circMPP6 and MPP6 exert distinct, partially opposing effects on NSCLC growth. In the context of MPP6 overexpression, circMPP6 counteracts tumor-promoting programs, highlighting functional divergence between circRNAs and their parental genes.

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Publication Details

Journal
Frontiers in Cell and Developmental Biology
Published
2026-02-03
DOI
https://doi.org/10.3389/fcell.2026.1722916
Primary Topic
Circular RNAs in diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Divergent roles of circMPP6 and its parental gene MPP6 in non-small cell lung cancer

Canhui Ou, Chengtao Yu, Weijuan Gao, Kangping Qiu et al.
Frontiers in Cell and Developmental Biology
Circular RNAs in diseases
article

Divergent roles of circMPP6 and its parental gene MPP6 in non-small cell lung cancer

Canhui Ou, Chengtao Yu, Weijuan Gao, Kangping Qiu, Fang Tian, Feng Pan
article en

Abstract

circMPP6 and MPP6 exert distinct, partially opposing effects on NSCLC growth. In the context of MPP6 overexpression, circMPP6 counteracts tumor-promoting programs, highlighting functional divergence between circRNAs and their parental genes.

Frontiers in Cell and Developmental BiologyVol. 14
Nanjing University of Chinese Medicine (CN), Shanghai Jiao Tong University (CN), Shanghai Chest Hospital (CN)
Openalex Percentile: Top 51%
Circular RNAs in diseases
DOIOpen Access PDFOpenAlex
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