Optimum electrical sinusoidal frequency stimulation to activate C-nociceptors
Sinusoidal frequencies between 3 and 8 Hz are better suited to activate C-nociceptors than stimuli above 10 Hz and are expected to facilitate C-nociceptor recruitment for their functional assessment in volunteers and chronic pain patients.
Authors
- Kiran Kumar Bali (ORCID: https://orcid.org/0000-0002-9503-1402)
- Roman Rukwied (ORCID: https://orcid.org/0000-0003-4118-497X)
- Martin Schmelz (ORCID: https://orcid.org/0000-0002-3536-8177)
- Divya Dileep
- Sabrina Soares
Institutions
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Bernstein Center for Computational Neuroscience Heidelberg-Mannheim (DE)
- University Medical Centre Mannheim (DE)
Publication Details
- Journal
- PAIN Reports
- Published
- 2026-02-17
- DOI
- https://doi.org/10.1097/pr9.0000000000001412
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00