Anti-Vascular Endothelial Growth Factor Drugs Restore Glial–Vascular Interaction in a Rat Model of Retinopathy of Prematurity

These findings suggest that pathological angiogenesis in ROP is mediated through VEGF- and mTORC1-dependent mechanisms. Anti-VEGF therapies may help restore glial-vascular interactions by reducing abnormal blood vessels in the ROP retina.

Authors

Toshihide Kashihara (ORCID: https://orcid.org/0000-0001-8787-5376)
Saori Deguchi
Tsutomu Nakahara
Akane Morita

Institutions

Kitasato University (JP)

Publication Details

Journal: Current Eye Research
Published: 2026-02-18
DOI: https://doi.org/10.1080/02713683.2026.2629431
Primary Topic: Retinopathy of Prematurity Studies
Type: article
Field-Weighted Citation Impact: 0.00

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article

Anti-Vascular Endothelial Growth Factor Drugs Restore Glial–Vascular Interaction in a Rat Model of Retinopathy of Prematurity

Toshihide Kashihara, Saori Deguchi, Tsutomu Nakahara, Akane Morita

Feb 18, 2026

Current Eye Research

Retinopathy of Prematurity Studies

article

Anti-Vascular Endothelial Growth Factor Drugs Restore Glial–Vascular Interaction in a Rat Model of Retinopathy of Prematurity

Toshihide Kashihara, Saori Deguchi, Tsutomu Nakahara, Akane Morita

February 18, 2026article en

Abstract

Current Eye Research

Kitasato University (JP)

Good health and well-being

Openalex Percentile: Top 51%

Retinopathy of Prematurity Studies

DOI Source OpenAlex

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Anti-Vascular Endothelial Growth Factor Drugs Restore Glial–Vascular Interaction in a Rat Model of Retinopathy of Prematurity — Toshihide Kashihara, Saori Deguchi, et al. · Current Eye Research (2026) | TGRS Research Map | TGRS