Severe bacterial infection in thalassemia patients: prevalence, predisposing factors, causative organisms and outcomes

Severe bacterial infections affected 20.7% of thalassemia patients in this cohort, mainly bacteremia due to <i>Klebsiella pneumoniae</i> and <i>Escherichia coli.</i> Major risk factors were severe anemia, prolonged splenectomy, diabetes mellitus, and iron overload with liver hemochromatosis.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-02-18
DOI
https://doi.org/10.3389/fmed.2026.1755729
Primary Topic
Hemoglobinopathies and Related Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Severe bacterial infection in thalassemia patients: prevalence, predisposing factors, causative organisms and outcomes

Kanda Fanhchaksai, Lalita Norasetthada, Sasinee Hantrakool, Pokpong Piriyakhuntorn et al.
Frontiers in Medicine
Hemoglobinopathies and Related Disorders
article

Severe bacterial infection in thalassemia patients: prevalence, predisposing factors, causative organisms and outcomes

Kanda Fanhchaksai, Lalita Norasetthada, Sasinee Hantrakool, Pokpong Piriyakhuntorn, Chatree Chai‐Adisaksopha, Teerachat Punnachet, Harit Thongwitokomarn, Nonthakorn Hantrakun, Ekarat Rattarittamrong, Piangrawee Niprapan, Thanawat Rattanathammethee, Adisak Tantiworawit, Sirichai Srichairatanakool, Ruttanaporn Taya
article en

Abstract

Severe bacterial infections affected 20.7% of thalassemia patients in this cohort, mainly bacteremia due to <i>Klebsiella pneumoniae</i> and <i>Escherichia coli.</i> Major risk factors were severe anemia, prolonged splenectomy, diabetes mellitus, and iron overload with liver hemochromatosis.

Frontiers in MedicineVol. 13
Chiang Mai University (TH)
Chiang Mai University, Faculty of Medicine, Chiang Mai University
Good health and well-being
Openalex Percentile: Top 51%
Hemoglobinopathies and Related Disorders
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