Efficacy and Safety of Combination Therapy With Immune Checkpoint Inhibitors and Chemotherapy With Gemcitabine and Nab‐Paclitaxel in Pancreatic Cancer: A Systematic Review

Combining ICIs with gemcitabine and nab-paclitaxel appears feasible and safe, with signals of improved efficacy compared with chemotherapy alone. However, evidence remains limited, and further large-scale trials are warranted to confirm survival benefits and optimize therapeutic strategies in pancreatic cancer.

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Publication Details

Journal
Cancer Medicine
Published
2026-02-01
DOI
https://doi.org/10.1002/cam4.71637
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and Safety of Combination Therapy With Immune Checkpoint Inhibitors and Chemotherapy With Gemcitabine and Nab‐Paclitaxel in Pancreatic Cancer: A Systematic Review

Hanye Sohrabi, Seyed Mohammad Ghavam, Nima Rezaei, Sina Azadnajafabad
Cancer Medicine
Pancreatic and Hepatic Oncology Research
article

Efficacy and Safety of Combination Therapy With Immune Checkpoint Inhibitors and Chemotherapy With Gemcitabine and Nab‐Paclitaxel in Pancreatic Cancer: A Systematic Review

Hanye Sohrabi, Seyed Mohammad Ghavam, Nima Rezaei, Sina Azadnajafabad
article en

Abstract

Combining ICIs with gemcitabine and nab-paclitaxel appears feasible and safe, with signals of improved efficacy compared with chemotherapy alone. However, evidence remains limited, and further large-scale trials are warranted to confirm survival benefits and optimize therapeutic strategies in pancreatic cancer.

Cancer MedicineVol. 15(2)
Universal Scientific Education and Research Network (IR), Children's Medical Center (IR), Tehran University of Medical Sciences (IR)
Openalex Percentile: Top 49%
Pancreatic and Hepatic Oncology Research
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