Population pharmacokinetics of amikacin in patients with a haematological disorder: A prospective, observational study
Amikacin target attainment was low in patients with a haematological malignancy treated empirically for FN, when pathogens with higher MICs are considered. Dosing optimisation may be needed to improve target attainment.
Authors
- Stefano Bassetti (ORCID: https://orcid.org/0000-0003-1729-1425)
- Verena Gotta (ORCID: https://orcid.org/0000-0001-6254-5207)
- Sereina Livia Müller
- Severin Bausch
- Michael Osthoff (ORCID: https://orcid.org/0000-0001-5439-957X)
- Sarah Dräger (ORCID: https://orcid.org/0000-0001-9410-7404)
- Sebastiaan D. T. Sassen (ORCID: https://orcid.org/0000-0002-4525-638X)
- Maja Weisser
- Katharina Rentsch
- Birgit C.P. Koch
- Jörg Halter
Institutions
- University of Basel (CH)
- Erasmus MC (NL)
- University Hospital of Basel (CH)
- University Children’s Hospital Basel (CH)
- Rotterdam University of Applied Sciences (NL)
Publication Details
- Journal
- Journal of Infection
- Published
- 2026-02-19
- DOI
- https://doi.org/10.1016/j.jinf.2026.106710
- Primary Topic
- Neutropenia and Cancer Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universität Basel
- Universitätsspital Basel