Cabotegravir plus Rilpivirine for Persons with HIV and Adherence Challenges
Monthly injections of long-acting cabotegravir-rilpivirine were superior to standard oral ART in reducing the risk of regimen failure among persons with HIV who had adherence challenges. (Funded by the National Institute of Allergy and Infectious Diseases; LATITUDE ClinicalTrials.gov number, NCT03635788.).
Authors
- Lawrence K. Fox (ORCID: https://orcid.org/0000-0001-7659-7809)
- Michael J. Stirratt (ORCID: https://orcid.org/0000-0001-5243-9312)
- Sara B. Sieczkarski
- JE Lake
- Kati Vandermeulen
- Kristina M. Brooks (ORCID: https://orcid.org/0000-0002-3832-8699)
- Kathie G. Ferbas (ORCID: https://orcid.org/0009-0005-8861-2240)
- S. S. Heath
- Cheryl Jennings (ORCID: https://orcid.org/0009-0002-3508-5350)
- E P Acosta
- Steven Shoptaw
- Charles S. Venuto
- Jose R. Castillo-Mancilla
- Chanelle Wimbish
- Paul Wannamaker
- Ronald D’Amico
- Tia Morton
- Omar Galáarraga
- Jonathan Z. Li
- Madison Green
- Aadia I. Rana
- Raphael J. Landovitz
- Ceora Beijer
- Pablo F. Belaunzaran-Zamudio
- Romina Collahua
- David Wohl
- Karen T. Tashima
- Kimberly Smith
- Rodica Van Solingen-Ristea
- Carl Fichtenbaum
- William Spreen
- Michael Dorosh
Institutions
- University of North Carolina at Chapel Hill (US)
- Brigham and Women's Hospital (US)
- Rush University Medical Center (US)
- National Institutes of Health (US)
- Harvard University (US)
- University of California, Los Angeles (US)
- Brown University (US)
- University of Alabama at Birmingham (US)
- The Coordinating Center (US)
- National Institute of Allergy and Infectious Diseases (US)
- Frontier Science & Technology Research Foundation, Inc. (US)
- Office of AIDS Research (US)
- University of Colorado Anschutz Medical Campus (US)
- University of Rochester (US)
- The University of Texas Health Science Center at Houston (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2026-02-18
- DOI
- https://doi.org/10.1056/nejmoa2508228
- Citations
- 2
- Primary Topic
- HIV/AIDS drug development and treatment
- Type
- article
- Field-Weighted Citation Impact
- 65.56