Genotypic-phenotypic discordance for cefiderocol against Enterobacter hormaechei
This study highlights a genomic-phenotypic discordance in an E. hormaechei isolate with borderline cefiderocol susceptibility. The findings underscore the risk of overestimating cefiderocol activity based solely on MIC values and emphasise the need for genomic resistance assessment in high-risk Enterobacterales.
Authors
- C. Hal Jones (ORCID: https://orcid.org/0000-0001-6275-0235)
- James Cruise
- Vineet Dubey
- Alessandro Gerada
- William Hope
- Alex Howard
Institutions
- University of Liverpool (GB)
- Royal Liverpool University Hospital (GB)
- Liverpool Heart and Chest Hospital (GB)
- Liverpool Hope University (GB)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2026-02-19
- DOI
- https://doi.org/10.1016/j.ijid.2026.108479
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00